APS
31st APS Annual Convention · 2019
Stress Neuroadaptations Following Heavy Marijuana Use: Phenomenology and Individual Differences Risk
- Gaylen Fronk
University of Wisconsin-Madison - Rebecca Gloria
San Francisco VA Medical Center - Kathryn Hefner
Uniformed Services University of the Health Sciences - John Curtin
University of Wisconsin-Madison
Abstract
We observed a pattern of increased stressor reactivity consistent with a stress neuroadaptation caused by marijuana use. Marijuana deprivation increased startle potentiation to threat in two tasks among heavy users. This increased reactivity was limited to individuals with high general startle reactivity (GSR), suggesting GSR may be a risk biomarker.
Substance Use and Abuse
