APS
2022 APS Annual Convention · 2022
Intergenerational Inheritance of N-Methyl-D-Aspartate (NMDA) Receptor Subunit Gene Expression Alterations in the Brain of Rats
- Claudia Paniagua-Ugarte
Radford University - Robert Sheehy
Radford University - Laura Griffith
Radford University - Jacob Eirich
Radford University - Shane McClafferty
Radford University - Pamela Jackson
Radford University - Dayna Hayes
Radford University
Abstract
Alteration of gene expression for subunit NMDA receptors, GRIN1 and GRIN2, in the brain of mammals is linked to schizophrenia. The symptomology presented due to this dysregulation manifests differently between genders and the etiology is uncertain. This study will examine heritability of these gene expression alterations as a potential explanation.
