APS
2022 APS Annual Convention · 2022
Reaction-Time Variability As a Specific and Sensitive Marker for ADD Symptoms
- Michael Aristodemou
Radboudumc, Donders Institute for Brain, Cognition and Behaviour - Nanda Lambregts-Rommelse
Radboud University Medical Center - Rogier Kievit
University of Cambridge
Abstract
We found that reaction-time variability was a specific correlate of symptom-severity in the inattention domain, but not in any other psychopathology domain. After testing four theoretical mechanisms, we found support for changes in locus-coeruleus norepinephrine function as a driver of reaction-time variability in children with higher inattention-symptom severity.
Psychopathology
