Distinct Neurocognitive Fingerprints Reflect Differential Associations with Problematic Substance Use

Substantial research links neurocognitive processes to substance misuse. Using a Bayesian non-parametric dimensionality reduction approach, we identified several neurocognitive fingerprints that represented person-specific variability in cognitive functioning. Individuals with a fingerprint characterized by poorer overall cognitive functioning across 11 different domains showed higher rates of substance misuse.