APS
2022 APS Annual Convention · 2022
Conditional and Moderated Effects of Polygenic Risk for Alcoholism on Alcohol Consumption Among African Americans with a History of Trauma
- Samantha Cassidy
Emory University - Whitney Barfield
Emory University - Chelsie Benca-Bachman
Emory University - Rameez Syed
Emory University - Seyma Katrinli
Emory University School of Medicine - Alicia Smith
Emory University School of Medicine - Abigail Powers
Emory University School of Medicine - Yara Mekawi
University of Louisville - Rohan Palmer
Emory University
Abstract
This study examined polygenic scores (PGSs) effects for alcohol use disorder (AUD), AUDIT-C, PTSD hyperarousal, and PTSD re-experiencing on alcohol consumption in the context of childhood and lifetime trauma. Childhood and lifetime trauma and the AUD PGS were significantly associated with alcohol consumption with evidence of gene x environment interplay.
Substance Abuse and Addiction
