Development of a Cortical Delay Discounting Assay: A Potential Biomarker of Externalizing Disorders

Across two adult samples, we developed and validated a cortical assay of impulsive decision-making using gray matter thickness. The cortical assay reliably measured delay discounting, drug use, and externalizing symptoms, indicating it may serve as a biomarker of susceptibility to psychiatric disorders characterized by impulsivity, addiction, and antisocial behavior.