APS
31st APS Annual Convention · 2019
Alterations in White Matter (WM) Microstructure and Increased Irritability in Bipolar Individuals and Their Relatives
- Caitlin Stavish
National Institute of Mental Health - Julia Linke
National Institute of Mental Health - Nancy Adleman
The Catholic University of America - Joelle Sarlls
National Institute of Neurological Disorders and Stroke - Kenneth Towbin
National Institute of Mental Health - Daniel Pine
National Institute of Mental Health - Ellen Leibenluft
National Institute of Mental Health - Melissa Brotman
National Institute of Mental Health
Abstract
Individuals with and at risk for bipolar disorder show comparable alterations in the microstructure of the superior corona radiata and anterior corpus callosum. This suggests altered white matter microstructure is a trait marker of bipolar disorder. Moreover, we see an association of aberrancies in white matter microstructure to elevated irritability.
Neuroscience
