APS

31st APS Annual Convention · 2019

Assessing Social Interaction through Chemogenetic Disruption of the Ventral Hippocampus and Orbitofrontal Cortex

Washington, DC · May 2019

Poster · Biological/Neuroscience

  • Anthony Alibro
    Post-baccalaureate Researcher
  • Tobi Abubakare
    Post-baccalaureate Researcher
  • Gloria Laryea
    Post-doctorate researcher
  • Yogita Chudasama
    Principal Investigator

Abstract

Social behaviors are often perturbed in neuropsychiatric disorders. Neuroimaging studies suggest increased activity in hippocampal and prefrontal cortical regions during socioemotional behavior. Using animal models, we examine the impact of disrupting hippocampal-prefrontal circuitry. In this study, we disrupted this pathway using DREADDS then tested animals on a Social interaction task.

Neuroscience

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