APS
31st APS Annual Convention · 2019
Dimensions of Psychopathology Are Dissociably Linked to Brain Structure in Youth
- Sophia Seonyeong Park
Lewis Katz School of Medicine, Temple University - Antonia Kaczkurkin
University of Pennsylvania - Aristeidis Sortiras
University of Pennsylvania - Tyler Moore
University of Pennsylvania - Monica Calkins
University of Pennsylvania - Matthew Cieslak
University of Pennsylvania - Adon Rosen
University of Pennsylvania - Kosha Ruparel
University of Pennsylvania - Daniel Pine
National Institute of Mental Health - Russell Shinohara
University of Pennsylvania - David Roalf
University of Pennsylvania - Ruben Gur
Philadelphia Veterans Administration Medical Center - Ruben Gur
University of Pennsylvania - Christos Davatzikos
University of Pennsylvania - Raquel Gur
University of Pennsylvania - Theodore Satterthwaite
University of Pennsylvania
Abstract
In this study we identified a dissociable relationship between dimensional psychopathology and brain structure using a sample of 1,394 youth. Increased fear symptoms were associated with reduced cortical thickness, and overall psychopathology was linked to global reductions in gray matter volume, suggesting potential biomarkers that may enhance interventions in youth.
Neuroscience
