APS
30th APS Annual Convention · 2018
Serial Ketamine Treatment Differentially Affects the Trajectories of Change in Depressive Rumination and Mood Scores in Major Depression
- Kavya Mudiam
UCLA Department of Psychiatry and Biobehavioral Sciences, UCLA - Nora Barnes-Horowitz
UCLA Department of Psychiatry and Biobehavioral Sciences, UCLA - Megha Vasavada
Ahmanson-Lovelace Brain Mapping Center, Department of Neurology, UCLA - Katherine Knarr
Ahmanson-Lovelace Brain Mapping Center, Department of Neurology, UCLA - Eliza Congdon
UCLA Department of Psychiatry and Biobehavioral Sciences, UCLA
Abstract
Changes in rumination sub-scales and the Hamilton Depression (HAMD) Rating scale were analyzed within treatment resistant depressed patients undergoing serial ketamine infusions. Rumination scores and HAMD scores improved across treatment. Rumination scores, unlike HAMD scores, remained stable post-treatment, suggesting that ketamine may have longer-term effects for improving certain depressive features.
Depression
