APS

30th APS Annual Convention · 2018

Oxytocin Improves Right Temporo-Parietal Junction Activity, Connectivity, and Behavior in Schizophrenia

San Francisco, CA · May 2018

Poster · Clinical Science

  • Lize De Coster
    San Francisco VA Medical Center
  • Lize De Coster
    University of California, San Francisco
  • Lisa Lin
    San Francisco VA Medical Center
  • Lisa Lin
    University of California, San Francisco
  • Nancy Fong
    San Francisco VA Medical Center
  • Nancy Fong
    University of California, San Francisco
  • Daniel H. Mathalon
    San Francisco VA Medical Center
  • Daniel H. Mathalon
    University of California, San Francisco
  • Joshua D. Woolley
    San Francisco VA Medical Center
  • Joshua D. Woolley
    University of California, San Francisco

Abstract

An fMRI study was conducted to assess oxytocin’s engagement of the neural network sub-serving theory of mind (ToM), and its ability to remediate the neurophysiological mechanisms underlying ToM ability in schizophrenia (SZ). We found that oxytocin increased right temporo-parietal activity in SZ and this increase correlated with improved ToM performance.

Social Cognition

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