APS
30th APS Annual Convention · 2018
Latent Classes of Cognition in Depressed Older Adults without Dementia Are Differentiated By Apoe e4 but Not Amyloid Positivity
- Ruth Morin
San Francisco VA Medical Center - Philip Insel
Lund University - Philip Insel
San Francisco VA Medical Center - Craig Nelson
University of California San Francisco - David Bickford
University of California San Francisco - Susan Landau
University of California Berkeley - Andrew Saykin
Indiana University School of Medicine - Michael Weiner
University of California San Francisco - Scott Mackin
San Francisco VA Medical Center - Scott Mackin
San Francisco VA Medical Center - Scott Mackin
University of California San Francisco
Abstract
Latent class analysis identified two classes of cognitive functioning in a sample of depressed older adults, with one class performing below the other on neuropsychological tests. Presence of the APOE e4 allele, but not amyloid positivity, depression severity, demographics, or treatment history, predicted membership in the lower cognitive functioning class.
Neuropsychology
