APS
29th APS Annual Convention · 2017
Prefrontal and Medial Temporal Lobe GABA and Glutamate: Neurobiological Correlates of Adolescent Sensation Seeking and Impulsivity
- Anna Seraikas
Neurodevelopmental Laboratory on Addictions and Mental Health - Emily Oot
Boston University School of Medicine - Emily Oot
Neurodevelopmental Laboratory on Addictions and Mental Health - Elena Stein
Neurodevelopmental Laboratory on Addictions and Mental Health - Carolyn Caine
Neurodevelopmental Laboratory on Addictions and Mental Health - Julia Cohen-Gilbert
Harvard Medical School - Julia Cohen-Gilbert
Neurodevelopmental Laboratory on Addictions and Mental Health - Sion Harris
Harvard Medical School - Sion Harris
Boston Children’s Hospital - J. Eric Jensen
Harvard Medical School - J. Eric Jensen
Neurodevelopmental Laboratory on Addictions and Mental Health - Jennifer Sneider
Neurodevelopmental Laboratory on Addictions and Mental Health - Jennifer Sneider
Harvard Medical School - Marisa Silveri
Harvard Medical School - Marisa Silveri
Neurodevelopmental Laboratory on Addictions and Mental Health
Abstract
Adolescent brain GABA and glutamate were measured in frontal lobe and medial temporal lobe (MTL). Higher MTL glutamate was significantly associated with greater sensation seeking and impulsivity. These data may help probe relationships between hippocampal/prefrontal coupling and risk-related behaviors that are developmentally adaptive, but that can become maladaptive during adolescence.
Adolescent
