APS
2026 APS Annual Convention · 2026
A Proposal to Probe Behavioral Deficits In Cognitive Flexibility (worse accuracy, reaction time, total earnings) Among Adults with Child-Onset Bipolar Disorder Using fMRI and Computational Modeling
- Logan Cummings
Harvard Medical School/ McLean Hospital - Daniel Dillon
Harvard Medical School/ McLean Hospital - Alessandro De Nadai
Harvard Medical School/ McLean Hospital - Daniel Dickstein
Harvard Medical School/ McLean Hospital
Abstract
Adults with child-onset bipolar disorder demonstrated worse cognitive flexibility (reaction time, accuracy; p<.043) than healthy adults during a reinforcement learning (RL) task during fMRI. Next steps: fit data to a RL model with a Rescorla-Wagner update rule and test group differences in learning rate, inverse temperature, and prediction-error-related brain activation.
