APS
2026 APS Annual Convention · 2026
Developmental Trajectories of Cortical Grey-White Matter Contrast and Psychopathological Symptoms Are Coupled across Adolescence
- Chloe Carrick
King's College London, Institute of Psychiatry, Psychology and Neuroscience - Linn Norbom
PROMENTA Research Center, Department of Psychology, University of Oslo - Dani Beck
PROMENTA Research Center, Department of Psychology, University of Oslo - Divyangana Rakesh
King's College London, Institute of Psychiatry, Psychology and Neuroscience - Christian Krog Tamnes
Division of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo - Christian Krog Tamnes
PROMENTA Research Center, Department of Psychology, University of Oslo - Delia Fuhrmann
King’s College London
Abstract
Using a longitudinal sample (N =11,859; ages 8-17) and bivariate latent growth models, we found that lower cortical grey-white matter contrast (GWC) related to higher internalising and externalising symptoms, and slower GWC development to greater increases in internalising symptoms. This indicates coupled change in brain microstructure and mental health.
