APS
2026 APS Annual Convention · 2026
Early Adversity Moderates the Relationship between Pro-Inflammatory Markers and Nucleus Accumbens-Hippocampal Resting-State Functional Connectivity in Adolescents with Major Depressive Disorder
- Jae Won Kim
Seoul National University College of Medicine - Mijeong Park
Seoul National University - Kyung Hwa Lee
Seoul National University
Abstract
Early adversity assessed by Early Trauma Inventory moderated the relationship between serum TNF-alpha levels and right nucleus-right hippocampus resting-state brain functional connectivity in 73 adolescents with major depressive disorder (51 girls, Mean age = 15), highlighting the need to consider early adversity when investigating neuroimmune mechanisms in adolescents with depression.
