Temporal Interference Stimulation for Optimized Sleep and Well-Being in Military Personnel with Posttraumatic Stress Disorder: A Proposed Clinical Trial

Virtual · October 2025

Poster · Clinical Science

Nicole Schlegel
Henry M. Jackson Foundation for the Advancement of Military Medicine
Nicole Schlegel
Center for the Study of Traumatic Stress, Department of Psychiatry, USUHS
Erin Maresh
Henry M. Jackson Foundation for the Advancement of Military Medicine
Erin Maresh
Uniformed Services University of the Health Sciences
Alexandria Pabst
Henry M. Jackson Foundation for the Advancement of Military Medicine
Alexandria Pabst
Uniformed Services University of the Health Sciences
Sarah Maggio
Henry M. Jackson Foundation for the Advancement of Military Medicine
Sarah Maggio
Uniformed Services University of the Health Sciences
Frances Gabbay
Henry M. Jackson Foundation for the Advancement of Military Medicine
Frances Gabbay
Uniformed Services University of the Health Sciences
Robin Bonomi
Uniformed Services University of the Health Sciences
Giulio Tononi
University of Wisconsin - Madison
Richard Davidson
University of Wisconsin - Madison
Vincent Capaldi
Uniformed Services University of the Health Sciences

Abstract

This proposed clinical trial addresses PTSD in active duty military personnel. Meditation training during wakefulness is combined with temporal interference stimulation during sleep to target cognitive flexibility and emotion regulation skills across the sleep-wake cycle. This intervention will inform best practices for effective sleep-based PTSD treatments in military health systems.

Sleep

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Temporal Interference Stimulation for Optimized Sleep and Well-Being in Military Personnel with Posttraumatic Stress Disorder: A Proposed Clinical Trial

Abstract

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