Mindful Awareness As Mechanism: Enhanced Mindfulness Following Psilocybin Predicts Obsessive-Compulsive Symptom Improvement

We examined the relationship between mindfulness and treatment outcome in a psilocybin trial for OCD. Increases in mindfulness significantly predicted OCD symptom reduction (β = -0.50, p = .003), indicating a potential role of mindfulness in the therapeutic effects of psilocybin for OCD.