Depression Is a Stronger Risk Factor for Alzheimer’s Disease Among Women Relative to Men in a Longitudinal Sample of over 26,000 Older Adults

Name: Depression Is a Stronger Risk Factor for Alzheimer’s Disease Among Women Relative to Men in a Longitudinal Sample of over 26,000 Older Adults
Start: 2025-05-24T00:00:00+00:00
Location: Washington, DC

Saturday, May 24, 2025 · Washington, DC

Submitted Talk · Saturday, May 24, 2025 · 4:30 PM – 4:45 PM ET

Subject Area: Clinical Science

Depression and sex influence Alzheimer’s disease. Cox proportional-hazards models examined effects of sex, age, and depression on impairment risk. In 26,362 adults, depression increased impairment risk by 74% in men (HR=1.74, p<.001) and 106% in women (HR=2.06, p<.001). For women, the effect of depression on impairment was significantly larger (p<.01).

Chairs & Discussants

Lauren RutterSpeaker
Indiana University
Lucas HamiltonAuthor
Augustana University
Skylar WilsonAuthor
Indiana University, Bloomington
Brea PerryAuthor
Indiana University, Bloomington
Anne KrendlAuthor
Indiana University, Bloomington

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Depression Is a Stronger Risk Factor for Alzheimer’s Disease Among Women Relative to Men in a Longitudinal Sample of over 26,000 Older Adults

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