Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder

Washington, DC · May 2025

Poster · Clinical Science

Ru Li
Tianjin Anding Hospital
Ru Li
Tianjin Anding Hospital
Yong Zhang
Tianjin Anding Hospital, Tianjin, China.
Shiyi Ji
Teachers College, Columbia University

Abstract

This study investigated the effects of functional remediation (FR) on serum BDNF/TrkB levels in euthymic bipolar disorder patients through a 12-week randomized trial. FR significantly improved serum BDNF/TrkB levels compared to treatment as usual (TAU). Changes in these biomarkers correlated with neurocognitive improvements, suggesting FR’s biomechanistic role in treatment.

Mood Disorders

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Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder

Abstract

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