APS

2024 APS Annual Convention · 2024

Inference on the Indirect Effect in the Presence of Missing Data: The Bias-Corrected Bootstrap Confidence Interval Results in Inflated Type I Error Rates When Implemented with Multiple Imputation Procedures

San Francisco, CA · May 2024

Poster · Methodology

  • Tristan Tibbe
    University of California, Los Angeles
  • Amanda Montoya
    University of California, Los Angeles
  • Catherine Crespi
    University of California, Los Angeles
  • Craig Enders
    University of California, Los Angeles

Abstract

Two different multiple imputation methods for mediation analysis on incomplete data implement the bias-corrected bootstrap confidence interval to determine the significance of the indirect effect. Our simulation study shows that this approach can result in elevated type I error rates, and alternative inferential techniques offer greater type I error control.

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