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2024 APS Annual Convention · 2024

Stress and Resilience Study Protocol: A Multiomics-Based Randomized Controlled Trial to Elucidate the Biology of ACEs and Test a Scalable Precision Stress Management Intervention for Normalizing Biopsychosocial Functioning and Enhancing Resilience

San Francisco, CA · May 2024

Poster · Clinical Science

  • Mathilda Von Guttenberg
    UCLA & California State University, Los Angeles
  • Lauren Kim
    UCLA Semel Institute
  • Sophia Myriam Schüssler-Fiorenza Rose
    Stanford University, CA, USA
  • Summer Mengelkoch
    University of California, Los Angeles, CA, USA
  • Daniel Moriarity
    University of California, Los Angeles
  • Jeffrey Gassen
    University of California, Los Angeles, CA, USA
  • Jenna Alley
    University of California, Los Angeles, CA, USA
  • Lydia Roos
    University of California, Los Angeles, CA, USA
  • Tao Jiang
    Northwestern University, Evanston, IL, USA
  • Arash Alavi
    Stanford University, CA, USA
  • Xinyue Zhang
    Stanford University, CA, USA
  • Dalia Perelman
    Stanford University, CA, USA
  • Tamar Kodish
    University of California, Los Angeles, CA, USA
  • Janice Krupnick
    Georgetown University, Washington, DC, USA
  • Michelle May
    Arizona State University, Tempe, AZ, USA
  • Katy Bowman
    Nutritious Movement, Carlsborg, WA, USA
  • Jenna Hua
    Million Marker Wellness, Inc., Berkeley, CA, USA
  • Joyce Liao
    Stanford University School of Medicine, CA, USA
  • Joyce Liao
    Stanford University School of Medicine, CA, USA
  • Alicia F. Lieberman
    University of California, San Francisco, CA, USA
  • Atul J. Butte
    University of California, Office of the President, Oakland, CA, USA
  • Atul J. Butte
    University of California, San Francisco, CA, USA
  • Patricia Lester
    University of California, Los Angeles, CA, USA
  • Patricia Lester
    University of California, Los Angeles, CA, USA
  • Shannon Thyne
    David Geffen School of Medicine, Los Angeles, CA, USA
  • Joan F. Hilton
    University of California, San Francisco, CA, USA
  • Michael P. Snyder
    Stanford University, CA, USA
  • George M. Slavich
    University of California, Los Angeles, CA, USA

Abstract

This proposal combines a cross-sectional study and longitudinal randomized controlled trial to address knowledge gaps in how Adverse Childhood Experiences (ACEs) and toxic stress affect adult health. Multiomics will be used to examine the impact of ACEs and test a precision stress management intervention to enhance individual and population resilience.

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