Heightened Negative Emotionality and the Moderating Effect of Childhood Trauma Severity on Alcohol Use Outcomes in Comorbid Alcohol Use Disorder and Post-Traumatic Stress Disorder

San Francisco, CA · May 2024

Poster · Clinical Science

Eva Cullins
NIH / NIAAA
Tommy Gunawan
National Institute on Alcohol Abuse and Alcoholism
Melanie Schwandt
National Institute on Alcohol Abuse and Alcoholism
Jeremy Luk
NIH-National Institute on Alcohol Abuse and Alcoholism
David George
National Institute on Alcohol Abuse and Alcoholism
Nancy Diazgranados
National Institute on Alcohol Abuse and Alcoholism
Vijay Ramchandani
National Institute on Alcohol Abuse and Alcoholism

Abstract

We measured negative emotionality, alcohol use, and childhood trauma in individuals with AUD with and without PTSD. There were 1,292 participants (537 female). Negative emotionality, alcohol use, and childhood trauma severity were higher in comorbid AUD and PTSD. Childhood trauma moderated the relationship between a comorbid diagnosis and alcohol-related outcomes.

Substance Abuse and Addiction

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Heightened Negative Emotionality and the Moderating Effect of Childhood Trauma Severity on Alcohol Use Outcomes in Comorbid Alcohol Use Disorder and Post-Traumatic Stress Disorder

Abstract

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