APS
2024 APS Annual Convention · 2024
Optimism and Pessimism Link to Neural Structures and Depressive Symptoms in Healthy Adolescents
- Tara Samson
University of California, San Francisco - Benjamin Sipes
University of California, San Francisco - Angela Jakary
University of California, San Francisco - Tiffany Ngan
University of California, San Francisco - Yi Li
University of California, San Francisco - Eva Henje
University of Umeå - Tony Yang
University of California, San Francisco - Olga Tymofiyeva
University of California, San Francisco
Abstract
We used diffusion MRI connectomics and self-report measures to investigate the correlates of optimism and pessimism in healthy adolescents. We observed strong associations between these traits and depressive symptoms with structural neural correlates in the amygdala, putamen, and vmPFC. We highlight the amygdalofugal pathway as a circuit for future study.
