APS
2023 APS Annual Convention · 2023
The Biology of Military Exposures and Aging: Connecting the Dots with Natural Language Processing
- Immanuel Samuel
Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, MD - Immanuel Samuel
Complex Exposure Threats Center of Excellence (CETCE), Department of Veterans Affairs, Washington, DC - Immanuel Samuel
War Related Illness and Injury Study Center (WRIISC), Department of Veterans Affairs, Washington, DC - Thomas Chacko
Complex Exposures Threats Center, Department of Veterans Affairs, Washington, DC, 20420 - Thomas Chacko
Center for Clinical Systems Biology, Rochester General Hospital, Rochester, NY, USA - Kamila Pollin
War Related Illness and Injury Study Center (WRIISC), Department of Veterans Affairs, Washington, DC - Kamila Pollin
Complex Exposure Threats Center of Excellence (CETCE), Department of Veterans Affairs, Washington, DC - Calvin Lu
War Related Illness and Injury Study Center (WRIISC), Department of Veterans Affairs, Washington, DC, 20420 - Calvin Lu
Complex Exposures Threats Center, Department of Veterans Affairs, Washington, DC, 20420 - Ryan Brewster
War Related Illness and Injury Study Center (WRIISC), Department of Veterans Affairs, Washington, DC - Ryan Brewster
Complex Exposure Threats Center of Excellence (CETCE), Department of Veterans Affairs, Washington, DC - John Barrett
Complex Exposures Threats Center, Department of Veterans Affairs, Washington, DC, 20420 - John Barrett
War Related Illness and Injury Study Center (WRIISC), Department of Veterans Affairs, Washington, DC, 20420 - Matthew Reinhard
War Related Illness and Injury Study Center (WRIISC), Department of Veterans Affairs, Washington, DC - Matthew Reinhard
Complex Exposure Threats Center of Excellence (CETCE), Department of Veterans Affairs, Washington, DC - Michelle Costanzo
Complex Exposure Threats Center of Excellence (CETCE), Department of Veterans Affairs, Washington, DC - Michelle Costanzo
War Related Illness and Injury Study Center (WRIISC), Department of Veterans Affairs, Washington, DC - Gordon Broderick
Complex Exposures Threats Center, Department of Veterans Affairs, Washington, DC, 20420 - Gordon Broderick
Center for Clinical Systems Biology, Rochester General Hospital, Rochester, NY, USA
Abstract
Natural language processing (NLP) enables large-scale extraction of expert-informed interpretations of clinical and experimental observations. We leverage this technology to survey and represent as a cause-and-effect network our current understanding of biological mechanisms linking complex military exposures to accelerated biological aging, which includes the exacerbating impact of cumulative military exposures.