APS

2023 APS Annual Convention · 2023

Is Olfactory Circuit Impairment Capable of Detecting Huntington's Disease?

Washington, DC · May 2023

Poster · Biological/Neuroscience

  • Maria Rudrud
    University of Wisconsin-Madison
  • Nathaniel Houghtaling
    University of Wisconsin-Madison
  • William Adams
    Loyola University Chicago
  • Alicia Henson
    University of Wisconsin-Madison
  • Jane Paulsen
    University of Wisconsin-Madison

Abstract

Olfactory performance declines throughout the Huntington's Disease (HD) course. PREDICT-HD participants were classified at their level of risk for symptom onset and completed the University of Pennsylvania Smell Identification Test. Odor detection accuracy declined with increased risk score and subsequent visits. Smell performance aligns with traditional measures of HD risk.

Smell

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