APS
2023 APS Annual Convention · 2023
Is Olfactory Circuit Impairment Capable of Detecting Huntington's Disease?
- Maria Rudrud
University of Wisconsin-Madison - Nathaniel Houghtaling
University of Wisconsin-Madison - William Adams
Loyola University Chicago - Alicia Henson
University of Wisconsin-Madison - Jane Paulsen
University of Wisconsin-Madison
Abstract
Olfactory performance declines throughout the Huntington's Disease (HD) course. PREDICT-HD participants were classified at their level of risk for symptom onset and completed the University of Pennsylvania Smell Identification Test. Odor detection accuracy declined with increased risk score and subsequent visits. Smell performance aligns with traditional measures of HD risk.
Smell