ICPS
2019 International Convention of Psychological Science · 2019
Unorthodox Circadian Rhythms in Mice Lacking Commensal Microbes
- Kenneth Onishi
University of Chicago - Vanessa Leone
University of Chicago - Andrew Maneval
University of Chicago - Carina Elvira
University of Chicago - Jonathan Riggle
University of Chicago - Betty Theriault
University of Chicago - Eugene Chang
University of Chicago - Brian Prendergast
University of Chicago
Abstract
Here we examine how the trillions of microbes that co-inhabit the body influence basic aspects of brain function and behavior. We document abnormally low amplitude circadian rhythms in germ free (axenic) mice which completely lack microbes. A normally-functioning circadian system thus requires microbial input.
Neuroscience
