The OXTR Single-Nucleotide Polymorphism rs53576 Moderates the Impact of Childhood Maltreatment on Empathy for Social Pain in Female Participants: Hints for Differential Susceptibility.

Paris, France · March 2019

Posters · Behavioral Genetics

Vera Flasbeck
LWL University Hospital, Department of Psychiatry, Psychotherapy and Preventive Medicine
Dirk Moser
Department of Genetic Psychology, Faculty of Psychology, Ruhr-University Bochum, Bochum
Robert Kumsta
Department of Genetic Psychology, Faculty of Psychology, Ruhr-University Bochum, Bochum
Brüne Martin
LWL University Hospital, Department of Psychiatry, Psychotherapy and Preventive Medicine

Abstract

We detected a moderating effect of the Oxytocin receptor polymorphism rs53576 on the impact of childhood trauma on empathy for psychological pain in a sample of 302 individuals (148 diagnosed with BPD). The results suggest that A-allele carriers are more sensitive towards early maltreatment and that maltreatment affects empathy.

Social Cognition

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The OXTR Single-Nucleotide Polymorphism rs53576 Moderates the Impact of Childhood Maltreatment on Empathy for Social Pain in Female Participants: Hints for Differential Susceptibility.

Abstract

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