Hematopoietic-Specific Deficiency of Duffy Antigen Receptor for Chemokines Promotes Insulin Resistance during Diet-Induced Obesity in Mice

Poster Session I

Keyword: Other

Abstract: Chronic inflammation is associated with obesity that originates from increased production of pro-inflammatory chemocytokines. Duffy antigen receptor for chemokines (DARC) plays an important role in regulating chemocytokines. In this study, we found that hematopoietic-specific, but not adipose-specific, deficiency of DARC promotes insulin resistance during diet-induced obesity in mice.

• Praneet Veerapaneni (Presenting Author)
• Ghaith Aboud (Author)
• Tyler Benson (Author)
• Ragheb Harb (Author)
• David Kim (Author)
• Mourad Ogbi (Author)
• Nicole Cyriac (Author)
• Mehek Sharma (Author)
• Hong Shi (Author)
• Ha Won Kim (Author)
• Neal Weintraub (Author)