Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder

Poster Session X

Sunday May 25, 2025 (09:00 - 10:00 ET)
Keyword: Mood Disorders

Abstract: This study investigated the effects of functional remediation (FR) on serum BDNF/TrkB levels in euthymic bipolar disorder patients through a 12-week randomized trial. FR significantly improved serum BDNF/TrkB levels compared to treatment as usual (TAU). Changes in these biomarkers correlated with neurocognitive improvements, suggesting FR’s biomechanistic role in treatment.