ICPS

2021 APS Virtual Convention · 2021

Impact of Medial Prefrontal Cortex and Hippocampus Inactivation on Sequential Order Memory

Virtual · May 2021

Posters · Neuroscience

  • Shang Lin Lee
    University of Connecticut
  • Brian Timmerman
    University of Connecticut
  • Riley Pflomm
    University of Connecticut
  • Nikita Roy
    University of Connecticut
  • Mahathi Kumar
    University of Connecticut
  • Etan Markus
    University of Connecticut

Abstract

Humans and rats with frontal or hippocampal dysfunction are impaired on temporal and order-based tasks. In a novel radial water-maze sequence task, rats could learn a "list" of up to seven items and made prospective errors. Inactivation of the hippocampus resulted in spatial confusion; prefrontal cortex inactivation increased retrospective errors.

Memory