APS
29th APS Annual Convention · 2017
Short Term Visual Memory Binding Deficits in Preclinical AD: Relation to Tau and Amyloid Burden
- Daniel Norton
Massachusetts General Hospital - Baena Ana
University of Antioquia - Guzman-Velez Edmarie
Massachusetts General Hospital/ Harvard Medical School - Francisco Lopera
University of Antioquia - Yakeel Quiroz
Massachusetts General Hospital
Abstract
The relation between visual short-term memory (VSTM) binding performance and Alzheimer’s disease (AD) biomarkers was explored in clinically unaffected individuals with the AD-causing PSEN-1 mutation. VSTM binding declined with age and was tightly correlated with tau PET levels (.63<r<.81). It holds promise as a diagnostic tool for preclinical AD.
Neuropsychology
